Drug product
LOSARTAN POTASSIUM TABLETS, USP 100 mg, Bulk, Rx only, For Further Manufacturing, Packing or Repackaging only, Manufactured by: Arrow Pharma (Malta) Ltd., Birzebbugia, Malta NDC 0591-3747-00
D-1102-2020
Product summary
- Event
- Event 85306
- Status
- Ongoing
- Classification
- Class II
- Quantity
- N/A
- Official record key
drug-enforcement:D-1102-2020
Official wording
Reason: CGMP Deviations: impurity for N-Nitroso-N-methyl-4-aminobutyric acid (NMBA) detected in the active pharmaceutical ingredient (API) used to manufacture finished products.
Code information: 1178533A, 1178534A, 1178535A, 1178536A, 1178537A, 1178538A, 1178539A, 1178540A, 1178541A, 1178542A, 1178543A, 1178544A, 1178545A, 1178546A exp 03/2020
Distribution pattern: Bulk product was distributed to one re-packager in California.
Derived failure modes
-
Foreign material or chemical contamination
impurity for N-Nitroso-N-methyl-4-aminobutyric acid (NMBA
-
Manufacturing or process control
CGMP Deviations